How To Detect Cancer?

Researchers found that damage to the cells that coat the mouth that can predict or foresee the damage that the same in the lungs which is the cause of the occurrence of cancer among smokers tuberculosis. Based on this mechanism, the examination will measure the mouth network molecular changes that cause lung cancer so that they can save the patient fell ill cancer risk of tuberculosis at the same time avoiding them is not comfortable of procedures used at this time.

A later time, the researchers hope will be present with the inspection procedures mouth swab smoker in order to predict or detect lung cancer, so avoid dangerous and painful biopsy on the lung. Even the word Dr. Li Mao, experts in the diseases of cancer, cervix and lungs in MD Anderson Cancer Center, University of Texas in Houston, this process may also lead to the examination that will detect other types of cancer. "Our study opens the door for increased ability to predict who has a greater likelihood fell ill cancer associated with tobacco.

Not only lung cancer, but also pancreas cancer, bladder and head and nape, which is also related to tobacco use, "said Mao. Smoking is a major cause of cancer tuberculosis but only about 10 percent of disease in smokers. The disease is usually rare show symptoms until later developed, which means that patients rarely diagnosed or treated until they are treated to late. The team is led by Mao wanted to find a way to monitor patients who use a similar drug - "Cox-2 inhibitor celecoxib, sold under the name" Celebrex "- in the hope that can prevent lung cancer.

They examine the two known genes that are able to prevent the development of cancer of FHIT and p16. At the meeting "American Association for Research Center in San Diego, the researchers claim they are looking for special damages on the two genes in the lung samples and mouth of the 125 smokers. Mao and his team examine the overlay network oral lungs - called "epithelium" - in 125 chronic smokers involved in the research. Status of two genes important that the cancer is analyzed. P16 and FHIT genes known or be damaged very early in the process of cancer development. The smoker's mouth swab network and tuberculosis at the beginning of the research and the lapse of three months later. The researchers analyze whether p16, FHIT or both have been pressed through a process called metilasi.

Metilasi pattern of the two types of genes that ago compared between the two networks. Comparisons show that the basic network metilasi in the p16 genes in the lungs seen in 23 percent of the participants, metilasi genes FHIT shown on 17 percent of the participants metilasi while the second type of genes found in 35 percent of the participants (smokers). Almost similar percentage also appear in the mouth, where there are metilasi p16 in 19 percent, FHIT in 15 percent, and metilasi both on 31 per cent.


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